T-cell and B-cell Receptor Antigen Mapping
Construct a comprehensive map linking trillions of T-cell receptors (TCRs) and B-cell receptors (BCRs) to millions of disease antigens. This map will facilitate antibody–antigen binding prediction, allowing the identification of target antigens based solely on immune cell DNA sequences.
Resources (5)
Scalable TCR synthesis and screening enables antigen reactivity mapping in vitiligo
Research and Reviews
TRAIT: A Comprehensive Database for T-cell Receptor-Antigen Interactions
Research and Reviews
Adaptive Biotechnologies
Company
R&D Gaps (1)
A better understanding of how the immune system interacts at the molecular level with threats and triggers is critical. This knowledge would enable the development of predictive tools and technologies to augment immune responses—improving interventions against infections, cancers, and autoimmune disorders.