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Pharm-ome Mapping

Systematically map drug–target interactions (the “pharm-ome”) to better predict drug efficacy, side effects, and repurposing

R&D Gaps (1)

Drug development is often hampered by failures related to absorption, distribution, metabolism, excretion, and toxicity (ADME/Tox). Improved predictive models for molecular interactions are essential for designing safer, more effective drugs, as well as evaluating the impact of environmental chemicals. Additionally, there is a significant gap in our knowledge of what exactly is present in foods and how these components affect human biology. A comprehensive mapping of the “foodome” and studies on food component functionality are needed to advance nutrition science and personalized dietary interventions.