Novel Therapeutic Approaches for Chronic Infections
New treatments for chronic infections (e.g., achieving a functional cure for hepatitis B) and novel monoclonal antibodies for diseases such as malaria.
New formulations (e.g., one time dose time release delivery) could improve delivery and compliance in low resource settings.
Resources (5)
Long-acting injectable malaria drug enters first-in-human study
Technology Seed
Footnotes to 10 technologies by Jacob Trefethen
Whitepapers and Essays
Making a “Miracle” HIV Medicine by Kamal Nahas
Whitepapers and Essays
R&D Gaps (1)
Many of the world’s most deadly diseases—such as tuberculosis, Group A Streptococcus, hepatitis C, hepatitis B, and syphilis—lack effective vaccines or cures. Additionally, the pace of developing effective, low-cost, therapeutics for emerging pathogens in low resource settings is too slow to meet global health needs. Malnutrition exacerbates susceptibility to disease and impedes recovery; food security is important especially for early child development. Understanding the basic science of malnutrition during development is important for the development of more effective interventions.